Paul Berg + Stanford Biochemistry Department

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Personal Reviews Berg, P., 2003. Moments of Discovery: My Favorite Experiments. J.Biol.Chem. 278: 40417-24 Berg, P. 2008. Moments of discovery Annual Review of Biochemistry 77: 15-44 Berg, P. 1981. Nobel Prize paper Dissections and Reconstructions of Genes and Chromosomes Science 213: 246 Public Policy papers • Berg, P., Baltimore, D., Boyer, H., Cohen, S., Davis, R., Hogness, D., Nathans, D., Roblin, R., Watson, J., Weissman, S., • Zinder, N. 1974. Potential biohazards of recombinant DNA molecules. Science 185: 303. Berg, P., Baltimore, D., Brenner, S., Roblin, RO., Singer, M. 1975. Asilomar conference on recombinant DNA molecules. Science 188: 991. • Berg, P., Singer, M. 1995. The recombinant DNA controversy: Twenty years later. PNAS 92, 9011-9013. • Berg, P., 2004. Asilomar and Recombinant DNA. website: http://www.nobel.se/chemistry/articles (August 26, 2004) • Berg, P., 1999. "Scientists and the Public: An Ambivalent Partnership" Useful Knowledge, Amer. Phil. Soc. 1999; 71-78: • Berg, P, 2006. Brilliant Science, Dark Politics, Uncertain Law. Jurimetrics 46 • Berg P, 2006. Origins of the human genome project: why sequence the human genome when 96% of it is junk? Am. J. Hum. Genet. 79: 4: 603-5 Books • Singer, M., Berg, P. 1990. Genes and Genomes: A Changing Perspective. Mill Valley (CA) University Science Books • Berg, P., Singer, M. 1992. Dealing with Genes: The Language of Heredity. Mill Valley (CA): University Science Books • Singer, M., Berg, P. 1997. Exploring Genetic Mechanisms. Sausalito, University Science Books. Berg, P, Singer, M. 2003 George Beadle: An Uncommon Farmer. Cold Spring Harbor Laboratory Press (NY) ,
Significant Publications from the BERG LAB
1.		Chamberlin, M. Berg, P. 1962. Deoxyribonucleic acid-directed synthesis of ribonucleic acid by an enzyme from Escherichia coli. PNAS 48: 81.
2.		Wood, WB. Berg, P. 1962. The effect of enzymatically synthesized ribonucleic acid on amino acid incorporation by a soluble protein-ribosome system from Escherichia coli.. PNAS 48: 94.
3.		Norris, AT., Berg P. 1964. Baldwin, AN., Berg, P. 1966/ Purification and properties of isoleucyl ribonucleic acid synthetase from E. coli. J. Biol. Chem. 241: 831. Mechanism of aminoacytl RNA synthesis: Studies with isolated aminoacyl adenylate complexes of isoleucyl RNA synthetase. PNAS 52: 330.
4.		Carbon, J., Berg, P., Yanofsky, C. 1966. Missense suppression due to a genetically altered tRNA. Cold Spring Harbor Symp. 31: 487.
5.		Soll, L., Berg, P. 1969. Recessive lethals: A new class of nonsense suppressors in Escherichia coli . PNAS 63: 392. Soll, L., Berg, P. 1969 Recessive lethal nonsense suppressor in Escherichia coli, which inserts glutamine. Nature 233: 1340.
6.		Jackson, DA., Symons, RH., Berg, P. 1972. Biochemical method for inserting new genetic information into DNA of Simian Virus 40: Circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli. PNAS 69: 2904.
7.		Mertz, J., Carbon, J., Herzberg, M., Davis, R., Berg, P. 1974. Isolation and characteri- zation of individual clones of Simian Virus 40 mutants containing deletions, duplications and insertions in their DNA. Cold Spring Harbor Symp. Quant. Biol. 39: 69 and in Viral Transformation and Endogenous Viruses (Kaplan, A.S., Ed.). New York: Academic Press
8.		Carbon, J., Shenk, TE., Berg, P. 1975. Biochemical procedure for production of small deletions in simian virus 40 DNA. PNAS 72: 1392. Shenk, TE., Carbon, J., Berg, P. 1976. Construction and analysis of viable deletion mutants of simian virus 40. J. Virol. 18: 664.
9.		Mulligan, RC., Howard, BH. , Berg, P. 1979 Synthesis of rabbit b-globin recombinant genome. Nature 277, 108-114.
10.		Goff, SP, Berg, P. 1979. Construction, propagation and expression of simian virus 40 recombinant genomes containing the Escherichia coli gene for thymidine kinase and a Saccharomyces cerevisae gene for tyrosine transfer RNA. J. Mol. Biol. 133, 359.
11.		Mulligan, RC. , Berg, P. 1980. Expression of a bacterial gene in mammalian cells. Science 209, 1422-1427. Mulligan, RC. , Berg, P. 1981. Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyl transferase. PNAS 78, 2072-2076.
12.		Okayama, H., Berg, P. 1982. High efficiency cloning of full-length cDNA. Molec. and Cell. Biol. 2, 161-170. Okayama, H., Berg, P. 1983. A cDNA-cloning vector that permits expression of cDNA inserts in mammalian cells. Mol. & Cell. Biol. 3, 2, 280-289.
13.		13. Fromm, M., Berg, P. 1983. SV40 early and late region promoter function are enhanced by the 72 base pair repeat inserted at distant locations and inverted orientations. Mol. and Cell. Biol. 3, 991-999.
14.		14. Jessberger, R., Berg, P.1991. Repair of deletions and double strand gaps by homologous recombination in a mammalian in vitro system. Molec. and Cell. Biol. 11: 445-457.
15.		15. Donoho, G., Jasin, M., Berg, P.1998. Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells. Molec & Cell Biology 18: 4070.

Personal story
An interview with Paul Berg https://www.youtube.com/watch?v=lT6wPAISDfY Protein Synthesis film https://archive.org/details/ProteinSynthesis P. Berg & Nate Oliveira film http://www.youtube.com/watch?v=ThgUyl1cAXI Web site for Berg description of first recombinant DNA http://www.dnalc.org/view/15022-How-the-first-recombinant-DNA-was-created-Paul-Berg.html Paul Berg on Science Policy https://www.ibiology.org/science-and-society/recombinant-dna-science-policy/ https://www.ibiology.org/science-and-society/contemporary-science-policy-issues/ An Oral History https://purl.stanford.edu/pp886df4273